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Respectful Insolence is a ScienceBlogs blog by a breast oncology surgeon and researcher which focuses on medical issues in woo and pseudoscience as well as cutting edge research in the author's field. It is written using the pseudonymous nom de blog "Orac", named after a sentient machine from Blake's 7. Orac was later "outed" as David Gorski.
Orac is best known for his posts examining vaccine hysteria and the "mercury militia" claims of a link between autism and vaccines. He has also had several Internet debates with disgraced fellow neurosurgeon Michael Egnor (now a Discovery Institute fellow) about Egnor's claims that modern neuroscience has provided evidence for a non-materialistic interpretation of mind.