Gene-centered view of evolution
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The "old world" view of Darwinian natural selection is that the fittest organisms are punched through, with little explanation as to why or how (other than they are the most useful/best adapted). The problem with this theory is that offspring are often as different as unrelated members of the species. The gene-centered view of evolution attempts to resolve the mystery as to why some alleles make it while others don't by looking at the segregation of genes over time. There is a rowers analogy that one can use to understand this concept, but it is best taken head-on.
 Attempt of explanation
Rather than look at the organism as a whole, this view holds that it is better to look at the benefit of each gene individually. This view also holds that the best genes will segregate by virtue of natural selection, thus creating the best organism for the conglomeration of genes provided. As lesser genes die off and are taken over by the fittest, the organism, as a whole, becomes more fit for survival.