John R. Brinkley
John Romulus Brinkley (later John Richard Brinkley; July 8, 1885 – May 26, 1942) was a
"medical doctor" quack practitioner from Kansas in the 1920s best known for promoting his "goat gland" therapy, transplanting goat testicles to cure impotence.
Seriously. We aren't kidding. Goat testicles.
 Poor lil' goats
He was a "medical doctor" because he had a medical diploma from the Eclectic Medical University of Kansas City, a notorious diploma mill whose mail-order degrees nonetheless gave him the right to practice medicine in a few states at the time, including Kansas. In any case, he set up a radio station to promote his goat therapy, where he also pioneered the practice of issuing prescriptions over the air to his listeners without any diagnosis (later popular on the Internet for obtaining Viagra).
The Federal Radio Commission (forerunner of the Federal Communication Commission) shut down his radio station, KFKB, in 1930 for promoting fraud and his license to practice medicine was revoked the same year by the state of Kansas because 43 deaths were attributed to his goat transplants. Undaunted, he sold the station (for a profit), and moved his radio operations to Mexico where he beamed his goat testicle transplant advertisements into the United States at 100,000 watts over the first "border blaster" station, XER (later XERA) in Ciudad Acuña.
 What's the matter with Kansas?
In 1930 he ran for governor of Kansas as an independent and almost won in a 3-way race (29.5% of the vote). He ran again as an independent in 1932 and almost won again with 30.6% of the vote. Unable to become governor of Kansas and stack the medical board with his own appointees, he moved his practice to Texas in 1933.
 On-a Mexican-whoa-whoa, radio
Meanwhile, his Mexican radio station started advertising a new therapy, mercurochrome injections and pills to cure impotence. (Mercurochrome is a topical antiseptic with a long history of safe and effective use as such, but it has no known use for impotence. The U.S. FDA removed it in the late 1990s from its Generally Regarded As Safe list as a topical antiseptic, mainly to throw out a bone to the anti-vaccination believers.)
In 1941 as World War II was getting underway, the Mexican government shut down his radio station for giving airtime to Axis sympathizers like Gerald Winrod and William Dudley Pelley, and he was out of business for good.
In 2016, a humorous documentary film was released on the life and times of John R. Brinkley, titled Nuts!.