2025 RationalWiki 'Oregon Plan' Fundraiser

There is no RationalWiki without you. We are a small non-profit with no staff—we are hundreds of volunteers who document pseudoscience and crankery around the world every day. We will never allow ads because we must remain independent. We cannot rely on big donors with corresponding big agendas. We are not the largest website around, but we believe we play an important role in defending truth and objectivity.

Fighting pseudoscience isn't free.
We are 100% user-supported! Help and donate $5, $10, $20 or whatever you can today with PayPal Logo.png!
Donations so far: $8765.50Goal: $10000

Draft:Pharmaceutical opioids

From RationalWiki
Jump to navigation Jump to search
Information icon.svg This is a draft that anyone is free to edit as they would a mainspace page.

Do not add categories to draft pages; use {{draft categories}} instead for a view.

Contributors should nominate draft articles for deletion only if they believe that the article is not applicable to RationalWiki's mission.

Articles involving living persons must conform to our guidelines on biographies of living people.

Opioids are substances, both natural and synthetic, that bind to opioid receptors.[1] These receptors are the same as those targeted by natural endorphins;[note 1] as such, opioids cause similar analgesic, sedative and euphoric effects.[2] Because of these effects, opioids are commonly used in medicine as painkillers and even anaesthetics.[3]

Notes[edit]

  1. A term that literally means endogenous morphine

References[edit]

  1. Hemmings, Hugh C.; Egan, Talmage D. (2013). Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application: Expert Consult - Online and Print. Elsevier Health Scienc,es. p. 253. ISBN 1437716792.
  2. Boecker H, Sprenger T, Spilker ME, Henriksen G, Koppenhoefer M, Wagner KJ, Valet M, Berthele A, Tolle TR (November 2008). "The runner's high: opioidergic mechanisms in the human brain". Cerebral Cortex. 18 (11): 2523–31. doi:10.1093/cercor/bhn013. PMID 18296435.
  3. Stromgaard K, Krogsgaard-Larsen P, Madsen U (2009). Textbook of Drug Design and Discovery, Fourth Edition. CRC Press. ISBN 9781439882405.