Talk:Codeine

"but it is a dissociative in large doses (similar to ketamine) "

In layman's terms? PFoster 18:39, 31 December 2007 (EST)

Uhhhh... it makes the world (and you) go byebye for a little while. I'm honestly not sure what to say -- this is one of those cases where "big words" are pretty much the only usable name for what's going on. EVDebs 18:47, 31 December 2007 (EST)

Ah, I get it - not dealing in my first language here, sometimes technical stuff escapes me. Is the big words entry a shot, ny dear? PFoster 18:56, 31 December 2007 (EST)

Nah, more of a "nudge nudge wink wink". Besides, we kind of need one -- it's one of the battlecries of anti-intellectual idiots everywhere. Particularly in English, where we have way more big words than most. EVDebs 19:41, 31 December 2007 (EST)

Delete or Merge?

Is this at all necessary? If there's a page for codeine & heroin should there be one for morphine, oxycodone, and fentanyl? I think this and heroin should be merged into an opioid article. Or this one should just be deleted. --PitchBlackMind 20:33, 20 June 2009 (UTC)

Eh, I don't know, why get rid of it? Oxycodone might make a good article... ħuman 20:45, 20 June 2009 (UTC)

Well that works fine then. I was working under the false impression that we don't want articles on random drugs. But if it's an acceptable area, I'm willing to write them all. --PitchBlackMind 20:53, 20 June 2009 (UTC)

I would say we don't want lots of them. So don't run amuck. ħuman 20:56, 20 June 2009 (UTC)

Yeah, I wasn't planning on going too crazy and writing about obscure drugs that the layman wouldn't recognize. Most of the major psychoactives are already up there anyway. Probably just Oxycodone, dissociative anesthetics, and Ecstasy.

Codeine is not a pro-drug

It's also not a derivative of morphine. Do some research. ^{— Unsigned, by: ‎Delysid / talk / contribs}

Onus is on you to show how its not, since it can be refined in another derivative of morphine. --Revolverman (talk) 02:30, 22 August 2012 (UTC)

The Lancet seems to think so... Aceⁱ⁹ 02:37, 22 August 2012 (UTC)

All I'm saying is that codeine and morphine are alkaloids from the opium poppy. They are two different substances.^{— Unsigned, by: Delysid / talk / contribs} 04:45, 22 August 2012 (UTC)

Yeah but I'll take the Lancet over your opinion. No offense. Aceⁱ⁹ 04:51, 22 August 2012 (UTC)

It's not opinion, it's a fact. The Lancet article said nothing about codeine being derived from morphine. They are both different naturally occurring substances. Erowid is a much better source of information than the Lancet. https://www.erowid.com/pharms/codeine/codeine.shtml https://www.erowid.com/pharms/codeine/codeine_faq.shtml

You mean like how Erowid says Most codeine found in pharmaceutical products today is synthetically produced via the methylation of morphine.? Aceⁱ⁹ 07:01, 22 August 2012 (UTC)

Erowid is a much better source of information than the Lancet Really? Better tell the academic world. Aceⁱ⁹ 07:02, 22 August 2012 (UTC)

Codeine and morphine are two different molecules. In the body, however, the liver metabolizes codeine into morphine as it breaks it down into waste products that are eliminated. 10mg codeine p.o. Is equivalent to 1.5mg morphine. C®ackeЯ 07:07, 22 August 2012 (UTC)

Yes, but the article makes no reference to the opium poppy.

Should it have? Also, please remember to sign your posts (see your talkpage). Peter ^{Rapidly running out of marmite} 07:48, 22 August 2012 (UTC)

Well yeah, if your going to mention codeine or morphine you should probably mention where they first came from. You know what, whatever, you win. This isn't really worth arguing over, it's just codeine.

For the record, here are the structures of morphine, codeine and heroin (and oxycodone for good measure). They would be considered derivatives of each other regardless of their synthetic routes because "derivative" refers most often to structural similarity rather than synthetic processes, and with the main common structural component being morphine, we would call them, collectively, morphine derivatives. But what do I know? I only have a Masters and a PhD in chemistry... ^{d hominem} 08:18, 22 August 2012 (UTC)

• 

  Codeine
• 

  Heroin

Sigh. sterile^{sporadic heavy hitter} 02:29, 23 August 2012 (UTC)