Genetically modified food or, more correctly, genetically engineered food or transgenic food is any food derived from organisms which had their genomes modified using the technique of DNA recombination.[wp] In this technique, genetic material is isolated from one organism and directly introduced into another. There is no requirement for the source and target organisms to be sexually compatible, and the transfer of genes can be highly specific, introducing only a single desired trait. This is unlike conventional breeding, which requires sexual compatibility and results in offspring with a mixture of traits from both parents.
The abbreviations GM (genetically modified) and GMO (genetically modified organisms) are commonly used. GMO can also include organisms genetically modified for purposes other than food, such as laboratory animals used in clinical research or non-food crops, such as cotton and poplars.
So far, all genetically modified foods on the market are plants. Genetically modified fish[wp] such as salmon have also been developed, but food regulators such as the USA's Food and Drug Administration have not yet approved these for farming and public consumption.
Opponents of GM food claim that its production has negative environmental impacts, that its consumption has adverse health effects, and that the companies that profit from it, notably the Monsanto corporation, are plotting to control the world food supply or achieve some other evil. This has resulted in intense public debate, even though the scientific consensus says very clearly that GMO food is safe  and the anti-GMO position is represented in the academic community by a tiny minority of researchers, many of them with ideological and financial conflicts of interest.
The most controversial instance of opposition to GM food is probably the case of Zambia. In 2002, the Zambian government opted to let its people starve in the midst of a region-wide crop failure by turning down a vast quantity of food aid in the form of GM corn, rather than feed them "GM poison".
 Pros and cons
Since DNA recombination is a very powerful technique which allows for almost arbitrary modifications to be introduced into the genome, GM food can have a variety of traits which are extremely unlikely to occur in nature (but not impossible) and can not be obtained using conventional methods of breeding. It is a way to short-circuit the millions of years of evolution and/or artificial selection which would be required for the desirable traits to arise spontaneously. This includes resistance to pests, viruses and herbicides, drought tolerance and improved nutritional value.
On the other hand, the newly introduced traits might disrupt the ecosystem surrounding a GM crop field, particularly when GM crops interbreed with wild relatives. This is not a problem unique to GMO crops; any crop with a new trait could potentially spread to the wild, whether it arose through random mutation or creation in a lab. There exists technology to prevent interbreeding, but it is not used due to its negative public perception. Most GM traits are also covered by patents, which means that cultivating a GM crop requires the payment of license fees to the company which commercialized the given trait. This has good as well as bad consequences: the bad ones are of course that only one company has a monopoly on the given traits, which increases prices and slows down adoption. The good consequence is that the company can demand additional environmental requirements for crop planting, such as mandating weed and insect refuges, which slow down or prevent the onset of resistance to GM traits.
 Common GM traits
The most common GM traits found in commercial crops focus on increasing yields by conferring immunity to pests, weeds and diseases. These traits translate into easily quantifiable financial gains for the farmer, so they were the first to be commercialized. The majority of GM crops have one or more of the following traits:
- Herbicide tolerance (HT). This type of trait confers immunity to a herbicide, typically glyphosate (also known as Roundup). Spraying with this herbicide kills the weeds without affecting the crop. This allows the farmer to easily avoid tillage. Tillage is normally done to control weeds, but accelerates soil erosion. HT crops usually require more herbicides than traditional ones, but the broad spectrum herbicides used on HT crops are typically less toxic than traditional selective herbicides, leading to a net reduction of the environmental footprint. Corn, canola, soy, and sugar beets are examples of common HT crops.
- Bt toxin production. Bt toxins are proteins produced by the soil bacterium Bacillus thuringiensis which are lethal to some species of insect pests, primarily moths and beetles. Bt extract is often used as an insecticide in organic farming. When an insect attempts to feed off a plant that produces a Bt toxin, it quickly dies. Bt crops require significantly less insecticides than their traditional counterparts. Note that there are now several different Bt toxin strains, each of which is lethal to a slightly different segment of the insect population and each of which has its own tracking number assigned to it by the EPA. Corn and cotton are examples of common Bt crops.
- Virus resistance. By introducing genes coding for viral coat proteins, plants can be made resistant to viruses. The best known example is the Rainbow variety of papaya, which is resistant to the papaya ringspot virus and is credited with saving the papaya farming industry in Hawaii. Unfortunately, the specific variety chosen to receive the ringspot virus resistance transgene turned out to be vulnerable to blackspot fungus, so now a second round of genetic modification is trying to breed in blackspot fungus resistance.
 GM traits newly in use
- Starch breakdown. A GM corn strain called Enogen contains a transgene for alpha amylase, the enzyme that breaks starch down into maltose. This reduces the amount of processing necessary to turn it into ethanol. As of mid-2014, Syngenta, the company that holds the patent on Enogen, has embarked on an incentive program to encourage farmers to plant it. Theoretically, this trait would also reduce the amount of processing necessary to turn it into corn syrup, but this possibility has not been commercially pursued.
- Non-browning. The Arctic Apple has the 4 genes that cause browning turned off. Since no transgenes were spliced into the apple's genome, Okanagan Specialty Fruits proudly touts "no frankenfood here!" (implying that they want to distance themselves from all those "nasty" GMO producers). The Arctic Apple was approved for commercial sale in the U.S. by the USDA and the FDA in early 2015.
- Improved handling characteristics. Simplot's harder-to-bruise Innate potato was approved by the USDA on 7-Nov-2014 and by the FDA on 20-March-2015. Due to public backlash, McDonald's has announced that they won't be using it for their French fries or hash browns, though.
 GM traits in development
There are also many other possible traits in the research stage or awaiting regulatory approval.
- Increased intrinsic yield. There is an ongoing research project called C4 Rice, which aims to create rice which uses the more efficient C4 photosynthesis pathway from corn, rather than the C3 photosynthesis native to rice. The C4 pathway requires only 1/3 the water as C3, meaning C4 rice could be grown in hot semi-arid environments and provide a stable food supply even during droughts. C4 plants also fix about an order of magnitude more CO2 than C3 plants, which could offset quite a bit of harm. If it ever proves successful, it may open the door to creating C4 wheat, C4 potatoes, C4 sugar beets, etc..
- Nitrogen fixation. There is a project to achieve symbiosis between nitrogen-fixing bacteria and cereals, a feature now restricted to legumes, which would obviate or significantly reduce the need for artificial fertilizer in their cultivation.
- Disease resistance. This ranges from blight-resistant potatoes to bananas resistant to fusarium wilt.
- Biofortified food has increased nutritional value or contains essential nutrients not present in traditional varieties. The best known example is Golden Rice, a humanitarian project to develop rice containing vitamin A (beta-carotene) in order to prevent vitamin A deficiency induced blindness in the developing countries. Other biofortified food plants currently under development include tomatoes containing anthocyanin (the antioxidant that makes blueberries blue), and soybeans containing omega-3 fatty acids.
- Altered starch characteristics. A GM potato strain called Amflora[wp] has the gene for amylose production turned off. This makes its starch waxier, making it more useful in industrial applications that call for amylopectin such as paper making.
- Improved digestion. The "Enviropig" was engineered to more efficiently digest plant phosphorus, eliminating the need to feed it phosphorus supplements.
 GM traits limited/abandoned
- Sterility. Known as Genetic Use Restriction Technology (GURT), or disparagingly known as "terminator genes", this would render the plants sterile. There are two types; sterility, and inactivation of genes if exposed to some chemical. These have been abandoned in agriculture by the biotech companies due to excessive backlash and biotech companies have contracts requiring farmers to not save seed. Arguably in the event of a national disaster, it's for the best that the supply chain is as simple as possible just in case, however there are some legitimate uses. It's helpful if you need to make sure that the plant doesn't breed with wild cousins, or if you want to make sure your crops don't sprout if they get wet. It does however see some use outside of agriculture; mosquitos can be bred en masse with an intentionally defective gene that only let's larvae survive in a lab, the defective mosquitos are released into an environment and breed naturally with the local mosquitos, and the next generation of mosquitos mostly die off. This will only suppress the mosquito population for a generation or so until it needs to be applied again, but so does spraying with DDT, and unlike DDT, it only harms mosquitoes.
- Frost resistance. One of the earliest attempts at producing a GM crop involved taking the gene for producing "anti-freeze" inside the winter flounder, and introducing it into a tomato. The hoped-for resistance to frost didn't appear (plant sap and fish blood don't freeze the same way), and the experiment was abandoned. This did not prevent legions of anti-GMO activists from using the "fishmato" as their poster child for Frankenfood.
- Delayed ripening. The now-discontinued Flavr Savr tomato. No fish genes.
 Controversy over GM food health
Several health concerns have been raised over GM foods:
 Lack of independent testing
Concern exists over lack of independent testing of GM foods. FDA regulations require new GM strains to be tested for things like allergen potential and toxicity, but these tests are allowed to be conducted by the manufacturers (with FDA oversight). While the concern is valid (striving for more studies furthers the scientific endeavor, whether GM or non-GM), the common argument that GMOs are not subject to independent testing whatsoever is false.
In 2012, the non-profit organization Biology Fortified began compiling the GENetic Engineering Risk Atlas (GENERA), an ongoing project to catalog peer-reviewed studies regarding GM health risks. As of April 2014, there are approximately 1080 studies on the list, about one-third of which were conducted from independently funded, non-manufacturer sources.
Additionally, there are no regulations requiring the testing of new crop strains produced by non-GM means, such as cross-breeding or induced mutation; thus, non-GM varieties are not tested at all. Historically, this has resulted in the disastrous release into the marketplace of the Lenape potato and celery containing excessive psoralens. To conclude, although testing that is funded by the manufacturers is not ideal (independently funded studies reduce the introduction of many forms of possible biases such as the sunk cost fallacy, confirmation bias, and/or bias blind spots), any testing is better than no testing (also consider that manufacturers have a vested interest in protecting their PR image, which when dealing with GMOs is already poisoning the well, and introducing harmful products could damage that image quickly).
 Food allergies
The rise in food allergies correlates to the rise of GM foods. A 2013 article in that bastion of scientific rigor, Elle magazine, claimed that the author's apparent allergy to corn wouldn't have happened if our corn wasn't genetically modified.
All that can be said is correlation does not equal causation. The rise in allergies is a common phenomenon in developed countries, even though the popularity of GM food varies wildly between them. Furthermore, new proteins introduced by genetic modification are required to have short digestion times in order to be found fit for human consumption, precisely because long-digestion proteins are potential allergens. Starlink corn is a famous example of a GM crop that was found unfit for human consumption (long before it was brought to market as cattle feed) on this basis.
Transgenic crops containing certain genes from other species can pose a serious food allergy risk if unlabeled. A gene from a cold-water fish to give fruits frost resistance, can trigger a reaction in someone allergic to sea food.  However, most transgenes code for proteins whose digestion times are too short to trigger an allergic reaction.
 Health implications of cross-pollination
The health implications of cross-pollination between GM crops and non-GM crops planted on other farms nearby have garnered some attention.
Starlink corn, a Bt corn variety using a different gene than Monsanto's, was declared unfit for human consumption because one of the introduced proteins (Cry9C) had a long digestion time and was thus a potential allergen. Starlink corn was, however, deemed fit for animal consumption, and was grown as cattle feed. Soon thereafter, Cry9C proteins were found in foodstuffs that were deemed fit for human consumption. Pollen containing the Bt genes had apparently hopped the fence into neighboring cornfields. While no cases of allergic reaction to Cry9C have been confirmed, this raises the spectre of other GM traits escaping isolation.
 GMO labelling laws
There are no mandatory labeling requirements for GM foods at the federal level in the United States. However, as of early 2014, Vermont has laws requiring foods containing genetically-modified crops to be labelled as such, which will go into effect in 2016. This specific law is being challenged in court. Two other states, Maine and Connecticut, have similar laws that will go into effect if and when other neighboring states also require GMO labelling. 30 more states have similar bills pending in their legislatures. The proponents of such labelling laws are mostly anti-GMO activists for whom labelling laws are but a first step. The opponents assert that such laws would make "no GMOs!" labels into selling points for a gullible public (much like "all natural!" labels do today), and would give no useful information about which genetic modifications are and aren't present.
European Union has very strict GMO labeling laws, mandating that every ingredient of the product that was produced from genetically modified organisms must be labelled, even if it contains no DNA and is chemically indistinguishable from its non-GM counterpart (e.g. oils and lecithin). Labeling is also mandatory in restaurant menus. Combined with the very high level of anti-GMO activity in Europe and the fact that only two GM traits are approved for local cultivation (one variant of Bt corn and the Amflora potato), this results in GM food being basically impossible to buy.
Labeling in Europe is not required for the meat, eggs and milk of animals fed with GM crops. Most European poultry and pigs are in fact fed GM cereals imported from the United States, as this is significantly cheaper than feeding them locally grown non-GM grain.
A common claim about European labeling laws is that cultivating GM crops in some area would automatically require honey produced in the same area to be labeled as genetically modified, because honey contains trace amounts of pollen (less than 0.5%). Given the anti-GMO hysteria, the label would make such honey potentially unmarketable in Europe. However, this is no longer true, as the rules were recently clarified; pollen is now considered as a "natural constituent" rather than an "ingredient" of honey, and so it only needs to be labelled if the honey contains more than 0.9% of GM pollen. Previous ruling from the European Court of Justice stipulated that pollen is an "ingredient" and therefore needs to be included on the ingredient list, and a label must be included if more than 0.9% of the pollen is genetically modified.
 The evidence so far
So far, all evidence is overwhelmingly in favor of safety of GM foods for human consumption. A wide variety of reputable organizations have stated that genetically modified foods are safe to eat, including the US National Academies of Sciences, the American Association for the Advancement of Science, the European Commission, and many more.
After years of cultivation, there seem to be no adverse health impacts associated specifically with them, and in some cases they can confer significant health benefits (e.g. Bt corn contains less carcinogenic fungal toxins than regular corn, Golden Rice has beta carotene which normal rice lacks, etc.). The continued insistence of anti-GMO activists that the science is uncertain is simply moving the goalposts.
Additionally, anti-GMO activists use the precautionary principle argument which states that as there is negative proof of the harm of GE foods (i.e. there is no absolute, ultimate proof that GM food is safe), GMOs should be opposed. Arguments of this nature are invalid, as any given technology cannot be proven to be safe in every possible imagined circumstance. Also, there is a chance that misinformation on the subject is harmful. People who would otherwise be fed are starved, being deprived of food being destroyed just because it is GMO.   
 Controversy over the environmental impact of GM food
Environmental concerns over GM food also exist. The scientific consensus over GM food crops and the environment is not as clear-cut as the consensus on GM food and health.
 Environmental impact of GM herbicide resistance
What is the impact on the environment where GM resistance leads to increased use of herbicides? So far there is very little data suggesting a major increase in herbicide use, and this completely ignores how glyphosate is far less toxic than many alternative herbicides (such as atrazine) - meaning that increases in the mass of herbicide used do not always translate to an increase in environmental impact. Sustained glyphosate use and poor management practices have led to some weeds becoming resistant to the herbicide. Proper weed management practices and careful use of selective herbicides can help mitigate this resistance.
The number of reported new cases of herbicide-resistant weeds has actually slightly decreased after the introduction of GM crops. Out of the 24 known glyphosate-resistant species, 13 were actually first documented in non-GM crops. As such, "superweeds" are a problem related to herbicide use and not directly to GM crop use.
It's important to keep in mind what a "superweed" is. A "superweed" is a plant that's resistant to the herbicide in use, allowing it to grow in the fields we'd rather use for crops, rather than a green monster that will overwhelm the whole world. Much like "superbugs" in hospitals, acquiring resistance to an herbicide is generally harmful to the plant if the herbicide is not present, as it requires the plant to spend additional energy and materials producing the proteins or other chemicals it uses to endure the herbicide, meaning "superweeds" are actually slightly weaker and less invasive that the, umm, garden variety. Otherwise the plant would likely have acquired the resistance without human intervention.
 Lateral gene transfer
What might happen if modified genes transfer laterally to other organisms? For example, herbicide resistance could transfer to related weedy species, producing herbicide resistant weeds - obviously an undesirable outcome. Occurrence of this gene flow has been confirmed in field studies, but so far it's uncertain whether this is a serious concern or not.[Who?] It should be noted that herbicide resistance is not unique to GM crops (for instance, imidazolinone-resistant canola was obtained using radiation breeding), nor does herbicide resistance in weeds require gene flow to occur.
There are technologies available to prevent the spread of transgenes in the environment by making the second-generation seed of GM plants sterile, but they are not used due to public opposition (see "Terminator seed technology" below).
There is also a misconception about potential "superweeds", where a wild cousin acquires a trait and the whole world is choking on canola/rapeseed. "Superweeds" are weaker than regular weeds as herbicide resistance is a detriment to most plants; it causes the plants to use up energy to survive under specific conditions, specifically when herbicide is present. Without the herbicide present, the tolerant plants tend to be pushed out by the intolerant plants.
 Legal implications of cross-pollination
What are the legal implications of cross-pollination between GM crops and non-GM crops planted on other farms nearby? While activists commonly claim that biotech companies (like Monsanto) will sue farmers for accidental contamination via cross-pollination, such lawsuits have not happened. In 2012, a group of organic farmers preemptively sued Monsanto for this very reason, but their case was thrown out when they were unable to present any evidence that supported their claims. It is unlikely that any judge would rule in favor of Monsanto in such a case, because the farmer would not obtain any undue benefit from the patented seeds.
Percy Schmeiser's case is often used as an example by activists - but the court found that he intentionally selected for GM traits in canola pollinated from a neighboring field by spraying his own field with glyphosate, which killed off all of his plants but left the pollination-planted ones intact, and then used the seed on his farm, planting a total of approximately 1,030 acres with the seed. Schmeiser attempted to claim that he was innocent and that the glyphosate-resistant crops appeared on his fields via pollination or from a passing truck's spillage, but the judge pointed out that all 1,030 acres were planted with glyphosate-resistant canola at a purity of 95-98%, far beyond the 0.5-2% typically seen from accidental contamination. Furthermore, the fact that Schmeiser intentionally sprayed glyphosate on his crops betrayed his knowledge of the seed, since glyphosate will kill any non-resistant plants. Monsanto won the lawsuit, but Schmeiser mounted a massive misinformation campaign online, which has led to a great many people being unaware of the true facts on this case.
GM traits are usually patented. While this draws a lot of criticism, this situation is in fact not any different from conventional breeding, where novel traits are also patentable. "Plant patents" have been protected by U.S. law since 1930. Several patents on first-generation GM traits are due to run out in the near future; the patent for first-generation RoundUp Ready soybean seeds, for example, will expire in 2015.
 Lack of biodiversity
When a GM crop is first introduced, the seeds are usually derived from a single strain. If this crop becomes immensely popular, you'll end up with multiple farmers planting one and only one strain of the crop, leaving all of these new crops vulnerable to disease. This happened with the Rainbow papaya: the strain chosen to receive the transgene for ringspot-virus resistance turned out to be vulnerable to the blackspot fungus. The problem can be avoided by breeding the GM trait into several varieties using conventional methods.
GM crops are not the only crops lacking biodiversity, nor is lack of biodiversity a new concern. The Great Irish Potato Famine occurred largely because Irish farmers planted only the "lumper" strain of potatoes; when the Potato Blight struck, it struck 'em all. McDonald's has long been criticized for its reliance on the Russet Burbank strain of potatoes for its French fries, to the exclusion of other strains.
This would likely be less of a problem if more GMO companies were able to enter into the market providing more variety of crops, or if the GMO crops could be allowed to hybridize with other strains. In other words, it's a problem caused by the restrictions on GMO crops.
 "Terminator seed" technology
A common myth is that the crops use "terminator seed" technology (technical name Genetic Use Restriction Technology, GURT) which causes the crops to yield sterile seeds. However, while testing has been conducted on GURT, there is actually a moratorium on its commercial use due to public opposition. Monsanto has also pledged not to use the technology.
Despite all the propaganda, GURT is actually a good thing because it stops planted GM crops from expanding into the wild - one of the few realistic concerns about GM crops. Seeds that cannot be saved for replanting are nothing new. Plants grown from traditional hybrid seed, in wide use since the 1920s, do not produce true copies in the second generation due to the existence of hybrid vigor. Therefore, new seed must be bought every year from a plant breeder to keep its desirable characteristics.
One of the few dangers of GURT would be in those rare cases if it were to fail. GURT is engineered as a genetic trait, which means it can and will mutate, and a germline mutation that deactivates the GURT geneplex would mean the seeds would be fertile. Were GURT actually implemented in real farms, the farmers would have to maintain the same vigilance they do today against GM seed or pollen escaping into the wild, just in case one of these deactivating mutations were to arise.
Vandana Shiva has claimed that GURT may somehow spread to wild plants and cause the total destruction of the Earth's biosphere. This is complete lunacy, since by definition sterility is not heritable.
 Environmental benefits of GM crops
Crops which are genetically modified to poison pests (such as Bt corn) reduce the need for pesticides to be sprayed on them, which benefits the environment. According to a decade-long study conducted in China on Bt cotton, since its introduction in 1997, pesticide use was reduced by half and the population of natural insect predators doubled (this is because pesticides kill harmful and helpful insects without discretion).. Another study, published in 2005 found that using GM crops that poison pests reduce greenhouse gas emissions by reducing the need for pesticide spraying. Additionally, GM crops which are modified for no-till or reduced-till farming systems (herbicide resistant crops) reduce the energy use in soil cultivation, again lowering overall greenhouse gas emissions. The EPA has required some insect resistant crops be regulated like chemical pesticides.  Developing countries see greater benefit to yields, and reductions in pesticide use, from using genetically modified crops, giving complaints about them just a touch of classism.
Some articles argue that the repression of GM foods by the environmental movement is the real problem. At least one high-profile environmentalist has changed his anti-GMO stance as a result of learning the actual science. (Did he simply sell out to Monsanto? A lot of anti-GMO bloggers and sites at the time thought so, but evidence has not been forthcoming.)
GM crops can of course be misused, and for this reason need oversight. However, after years of cultivation, there seem to be no adverse impacts associated specifically with them, and in many cases they confer significant environmental benefits. The continued insistence of anti-GMO activists that the science is uncertain is simply moving the goalposts.
 Pseudoscience regarding GM food
Attacks on GM food often utilize pseudoscience.
 GM crops and health
The most prevalent claim is that all GMOs are harmful to health and cause a variety of illnesses and disorders: cancer, autism, reproductive problems, infant mortality, liver problems and many other things. These claims are totally false and on the same level as vaccine hysteria. Many of these claims are spread on the internet by cranks (such as NaturalNews, Joseph Mercola, FoodBabe.com, and the Institute for Responsible Technology); more generally by groups like the non-GMO project; and by environmental groups such as Greenpeace and the Sierra Club. Some activists went as far as dressing up in Hazmat suits while destroying GM crops to make it look as if researchers needed protection against the plants. 
The scientific consensus says that there are no generic health risks common for all GM food. Any possible harm can only come from a specific engineered trait. This view is shared by the World Health Organization, the Food and Agriculture Organization of the United Nations, the European Food Safety Agency, the International Council for Science, the U.S. National Academies of Science, and almost all national scientific bodies. According to one metastudy which included 12 long-term studies and 12 multigenerational studies: "The studies reviewed present evidence to show that GM plants are nutritionally equivalent to their non-GM counterparts and can be safely used in food and feed."
 Seed fertility
Anti-GMO activists often say that GM seeds are infertile. This refers to Genetic Use Restriction Technology, dubbed "terminator seed", which renders the second generation seed of a plant infertile. (See "Terminator seed technology" above.) This would prevent the farmer from saving seed, which currently is a requirement enforced using legal means.
GURT was never commercialized and work on it was abandoned in 1999, largely due to public backlash instigated by the anti-GMO campaigners. Ironically, it would solve one of the few real problems with GM crops, namely the transfer of GM traits into wild relatives. It would also enable the safe use of GM plants to produce pharmaceutically active compounds.
 Influence on bees
There are also claims that Bt crops are responsible for bee deaths and colony collapse disorder (CCD). This is false.
Bt toxin is harmful to some Lepidoptera (butterflies / moths) and Coleoptera (beetles) which feed directly on the plant, though several strains are becoming resistant to Bt toxin -- and even then, the effects on butterflies is not significant and quite negligible.   Beetles and certain species of butterflies tend to be pests themselves, after all, and were the target of the Bt toxin in the first place.
Bt toxin is not at all harmful to bees, which are in the order Hymenoptera. A meta-analysis of 25 studies found that there is no detectable harm to bees arising from the use of Bt crops. In fact, imidacloprid, a pesticide used on corn crops, is toxic to bees; and the whole point of Bt corn crops is that they need to be sprayed with less pesticide. And a meta-analysis has confirmed this. 
Note that traditional pesticides also kill butterflies and beetles, and that the Bt toxin is also used as a pesticide on both conventional non-GMO crops and organic crops. Some evidence however, has shown that BT Maize does cause slight learning disturbances in bees.  However, this effect has only been detected with concentrations of Bt toxin at 5000 ppb, and it's unlikely for this effect to show in natural conditions. 
 Influence on rodents
Most GMO maize is commodity corn, i.e. corn not meant to be eaten directly but used as source for starch. Although GMO maize is harmless for human and mammal consumption, paranoia in China claimed that several models of Pioneer maize and soy is affecting the reproduction of rats and Chinese pygmy hamsters and thereby affecting the food chain. This was due to a 2010 Russian study.
Another study released in the journal Food and Chemical Toxicology, conducted by Gilles-Eric Séralini, supposedly showed a link between GM maize and a higher incidence of cancer in the Sprague–Dawley strain of rat. The study was later retracted by the journal after a large amount of scientists protested its poor quality and its "inadequate data to support its conclusions" (specifically that the sample size was too small and the type of rat used was already prone to tumors). This latter retracted study is the one most often cited to back the pseudoscientific claim that GMOs cause cancer.
 Farmer suicide in India
Some anti-GMO activists, like Vandana Shiva, also claim that Bt cotton in India ruins small farmers and drives them to suicide. Bt cotton in India is not a substantial factor in farmer suicides, which started rising 5 years before its introduction. In fact, a long-term study on the economic impacts of Bt cotton in India showed that Bt cotton has increased yields, profits, and the living standards of smallholder farmers.
 See also
- Norman Borlaug, credited as the father of the Green Revolution.
- Bill Nye 
- Neil deGrasse Tyson
- Mark Lynas, British environmentalist, journalist, and author. Formerly anti but switched his position.
- Richard Dawkins, Evolutionary biologist.
- Steven Novella, Senior Fellow and Director of the JREF’s Science-Based Medicine project. 
- Ben Goldacre, Doctor, skeptic and science writer.
- Michael Shermer. Author and skeptic.
- PZ Myers Blogger and scientist.
- The Royal Society. British science group.
- Brian Dunning Legally-challenged skeptic and podcaster.
 Genetic modification is a tool which could be used for good or evil
- American Academy of Environmental Medicine, an anti-GMO, pro-pseudoscience group of physicians.
- Michael Pollan, a prominent American journalist and author
- Gilles-Eric Séralini, who published a study claiming Roundup Ready corn causes cancer
- Irina Ermakova, who published a study claiming Roundup Ready soy causes reproductive problems
- Judy Carman, who published a study claiming GM maize and soy inflames pig stomachs
- Greenpeace, an international environmentalist organization which campaigns against GM food
- Organic Consumers Association, who also oppose GMOs.
- John Fagan, head of the multinational for-profit testing company Global ID/Genetic ID
- Jeffrey Smith, who runs the Institute for Responsible Technology.
- Union of Concerned Scientists
- David Icke, conspiracy theorist.
- Prince Charles, heir to the British Throne.
- Deepak Chopra, quantum woo specialist.
- Vandana Shiva
- Jane Goodall, the chimp lady.
- NaturalNews. Need we say more?
 Anti-GMO films
- GMO A Go Go, a libertarian flavored anti-GMO propaganda film
- Seeds of Death, a right-wing anti-GMO propaganda film
- Food, Inc, another anti-GMO film (although also about other stuff) but from a left-wing point of view
- GMO OMG, an hard green 'racial' anti-GMO propagnda film
- What’s the latest on genetically modified foods?, from Cecil "Straight Dope" Adams
- GMO Skepti-Forum, a closed Facebook group for the scientific discussion of GMOs
- GMOLOL, an open Facebook group for laughing at anti-GMO hysteria
- ↑ The genomes of nearly all important crops are heavily modified with respect to their wild ancestors through the process of selective breeding and in many cases also by other techniques such as hybridization and mutation breeding, so using the term "genetically modified" specifically to label recombinant organisms is something of a misnomer.
- ↑ http://www.agbioforum.org/v8n4/v8n4a02-sedjo.pdf
- ↑ A. Nicolla, A. Manzo, F. Veronesi, D. Rosellini, An overview of the last 10 years of genetically engineered crop safety research Critical Reviews in Biotechnology, 2014, 34(1), 77-88
- ↑ Gilles-Eric Séralini, tied to a Big Placebo company and funded by anti-GMO organizations, is a notable example.
- ↑ Gorski, David More bad science in the service of anti-GMO activism Science-Based Medicine
- ↑ Labels for GMO Foods Are a Bad Idea Scientific American
- ↑ Kloor, Keith GMO Opponents Are the Climate Skeptics of the Left Slate
- ↑ BBC News: Zambia refuses GM 'poison'
- ↑ Better dead than GM-fed?, The Economist, 19-Sept-2002. Claims that the cross-pollination threat to Zambia's crop exports might have been partly to blame.
- ↑ Namely, Variety GURT, which renders sterile all seed produced by the plant. Sterile seeds can't crossbreed with anything. Called "terminator seed technology" by its opponents, it attracted so much misguided outrage that it has been abandoned, as described in the Controversy section later in this article.
- ↑ In 2010, 16% of U.S. corn had the Bt trait, 23% had the HT trait, and 47% had both. Source: http://usda.mannlib.cornell.edu/usda/nass/Acre/2010s/2010/Acre-06-30-2010.pdf
- ↑ ISAAA Brief 43-2011. Executive Summary: Global Status of Commercialized Biotech/GM Crops: 2011
- ↑ Hayes' Handbook of Pesticide Toxicology
- ↑ Transgenic Virus-Resistant Papaya: The Hawaiian ‘Rainbow’ was Rapidly Adopted by Farmers and is of Major Importance in Hawaii Today, on APSnet
- ↑ U.S. Approves Corn Modified for Ethanol, NY Times, 12-Feb-2011
- ↑ Get Paid to Plant Enogen, AgWired, 27-Aug-2014
- ↑ Acrtic Apples
- ↑ Simplot's website. Like the Arctic Apple, Simplot doesn't use transgenes from other unrelated species, but instead manipulates the potato genes directly.
- ↑ .S.D.A. Approves Modified Potato. Next Up: French Fry Fans., The New York Times, 7-Nob-2014
- ↑ INNATE™ Potato Receives FDA Safety Clearance
- ↑ McDonald's rejects Simplot's genetically modified potato, Idaho Statesman, 15-Nov-2014
- ↑ International Rice Research Institute: C4 Rice. As of December 2012, the C4 Rice Consortium apparently hasn't yet isolated the genes responsible for C4 photosynthesis.
- ↑ John Innes Center: Major investment to persuade bacteria to help cereals self-fertilise
- ↑ BBC News: Blight-resistant GM potatoes field trial begins
- ↑ The Age: Disease-resistant banana plant developed
- ↑ http://www.goldenrice.org/
- ↑ Genetically-modified purple tomatoes heading for shops, BBC News, 24-Jan-2014
- ↑ DSM and Monsanto to commercialize soybean oil rich in omega-3 SDA. But will anti-GMO sentiment hinder its progress?, Food navigator-usa, 8-April-2013
- ↑ http://www.uoguelph.ca/enviropig/
- ↑ Florida Health Officials Hope To Test GMO Mosquitoes This Spring, NPR
- ↑ Studies with independent funding, Biology Fortified, 10-June-2014
- ↑ The case of the poison potato, boingboing, 25-March-2013
- ↑ Unintended Health Effects: A Conventionally-Bred Celery Cultivar, National Academies Press, 2004
- ↑ The Bad Seed: The Health Risks of Genetically Modified Corn, in the Hair and Beauty section of the 24-July-2013 Elle. Rebuttal on Slate: No, You Shouldn’t Fear GMO Corn, 7-Aug-2013.
- ↑ 35.0 35.1 http://www.public.iastate.edu/~rhetoric/105H16/cofp/tmrcofp.html
- ↑ Taco Bell Recalls Shells That Used Bioengineered Corn
- ↑ CDC, National Center for Environmental Health. Investigation of Human Health Effects Associated with Potential Exposure to Genetically Modified Corn: A Report to the U.S. Food and Drug Administration from the Centers for Disease Control and Prevention. Atlanta,GA:Centers for Disease Control and Prevention, 2001.
- ↑ Vermont Lawmakers Pass GMO Labeling Bill; Governor Expected To Sign, Huffington Post, 24-April-2014
- ↑ http://www.abajournal.com/news/article/food_manufacturers_challenge_vermonts_gmo_law/
- ↑ Maine becomes second state to require GMO labels, The Washington Post, 10-Jan-2014]
- ↑ Genetic Literacy Project Infographic: Is labelling GMOs really about our “Right to Know”?
- ↑ http://www.beuc.org/press-media/news-events/european-parliament-vote-keep-lid-gm-pollen-honey
- ↑ Peer Reviewed Publications on the Safety of GM Foods
- ↑ Studies for GENERA (as of 5/27/13, there are exactly six hundred studies in this list)
- ↑ Safety of Genetically Engineered Foods: Approaches to Assessing Unintended Health Effects
- ↑ Quote: 'The science is quite clear: crop improvement by the modern molecular techniques of biotechnology is safe.'
- ↑ A decade of EU-funded GMO research
- ↑ Biotech-Now: Moms Urged to Subscribe to the ‘Precautionary Principle’ on GMOs
- ↑ Institute of Science in Society: Use and Abuse of the Precautionary Principle - this is a somewhat outdated defense of the use of the precautionary principle being applied to GE technology.
- ↑ http://news.bbc.co.uk/2/hi/africa/2371675.stm
- ↑ http://www.lusakatimes.com/2014/06/07/lunanshya-council-destroys-bokomo-cornflakes-containing-traces-gmo/
- ↑ The True Story About Who Destroyed a Genetically Modified Rice Crop, Mark Lynas, 26-Aug-2013
- ↑ Facts about Glyphosate-Resistant Weeds
- ↑ Where are the super weeds?
- ↑ Watrud, L.S. et al., Evidence for landscape-level, pollen-mediated gene flow from genetically modified creeping bentgrass with CP4 EPSPS as a marker. Proceedings of the National Academy of Sciences, October 5, 2004, vol. 101, no. 40, pp. 14533-14538.
- ↑ OSGATA v. Monsanto decision
- ↑ Federal Court (Canada) decision - Monsanto Canada Inc. v. Schmeiser
- ↑ swissinfo.ch: New e-licencing platform highlights patent debate - note that this article is not about GM traits, since neither of the two traits approved for cultivation in the EU belongs to Syngenta.
- ↑ GURT overview.
- ↑ "Is Monsanto Going to Develop or Sell "Terminator" Seeds?", paragraph 3
- ↑ Hybrid varieties and saving seed
- ↑ Stolen Harvest: The Hijacking of the Global Food Supply By Vandana Shiva
- ↑ Widespread adoption of Bt cotton and insecticide decrease promotes biocontrol services Nature
- ↑ GM Crops: The Global Economic and Environmental Impact - The First Nine Years AgBioForum
- ↑ A Meta-Analysis of the Impacts of Genetically Modified Crop Wilhelm Klümper, Matin Qaim
- ↑ Prospect Magazine: The real GM food scandal
- ↑ Leading Environmental Activist’s Blunt Confession: I Was Completely Wrong To Oppose GMOs
- ↑ Like this one: Uncovering the Real Story Behind the 'Conversion' of Mark Lynas from Climate Change Journalist to Cheerleader for Genetically Modified Foods, on AlterNet
- ↑ NaturalNews: Shock findings in new GMO study: Rats fed lifetime of GM corn grow horrifying tumors, 70% of females die early
- ↑ Institute for Responsible Technology: Are Genetically Engineered Foods Promoting Autism?
- ↑ Institute for Responsible Technology: Health risks of GMOs
- ↑ Greenpeace: What's wrong with genetic engineering (GE)?
- ↑ Sierra Club: Genetic Engineering
- ↑ http://www.theland.com.au/news/agriculture/cropping/general-news/greenpeace-gm-wheat-hazmat-suits-theatre/2268325.aspx?storypage=1
- ↑ http://www.geneticliteracyproject.org/wp/wp-content/uploads/2013/10/Nicolia-20131.pdf
- ↑ WHO: 20 questions on genetically modified foods
- ↑ ICSU report on GM food
- ↑ http://www.nationalacademies.org/webextra/crops/
- ↑ Snell, Chelsea; Bernheim, Aude; Berge, Jean-Baptiste; et al ScienceDirect: Assessment of the health impact of GM plant diets in long-term and multigenerational animal feeding trials: A literature review
- ↑ Hermosillo, Maribel Monsanto's GMO Seeds Are Actively Cultivating Cultural Genocide PolicyMic
- ↑ http://www.monsanto.com/newsviews/Pages/terminator-seeds.aspx
- ↑ http://fbae.org/2009/FBAE/website/our-position-gene-use-restriction-technologies.html
- ↑ http://www.nature.com/news/2001/010912/full/news010913-12.html
- ↑ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189815/
- ↑ http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0001415
- ↑ http://acsh.org/2014/11/meta-analysis-shows-gm-crops-reduce-pesticide-use-37-percent/
- ↑ http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0028174
- ↑ Ramirez-Romero et al., Does CrylAb protein affect learning performances of the honey bee Apis mellifera L. (Hymenoptera, Apidae)?, Ecotoxicology and Environmental Safety, January 2008
- ↑ http://www.gmwatch.org/latest-listing/1-news-items/12160-gm-soy-linked-to-sterility-infant-mortality
- ↑ Butler, Dnecla (25 September 2012). "Rat study sparks GM furore". http://www.nature.com/news/rat-study-sparks-gm-furore-1.11471.
- ↑ Casassus, Barbara (Nov 29, 2013). "Study Linking Genetically Modified Corn to Rat Tumors Is Retracted". http://www.scientificamerican.com/article/study-linking-genetically-modified-corn-to-cancer/.
- ↑ The Selling of the Suicide Seeds Narrative, Discover blogs, 7-Jan-2014
- ↑ http://www.ifpri.org/sites/default/files/publications/ifpridp00808.pdf
- ↑ Kathage, J.; Qaim, M. (2012). "Economic impacts and impact dynamics of Bt (Bacillus thuringiensis) cotton in India". Proceedings of the National Academy of Sciences 109 (29): 11652–6. PMC 3406847. PMID 22753493. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3406847.
- ↑ http://www.patheos.com/blogs/danthropology/2015/02/bill-nye-says-science-changed-his-anti-gmo-views/
- ↑ https://www.youtube.com/watch?v=1ecT2CaL7NA
- ↑ https://www.facebook.com/neiltyson/posts/10204439688771816
- ↑ http://www.skepticalraptor.com/blog/wp-content/uploads/2013/06/Dawkins-letter-Prince-Charles.pdf
- ↑ http://www.randi.org/site/index.php/swift-blog/2225-no-health-concerns-for-gmo.html
- ↑ More bad science in the service of anti-GMO activism
- ↑ [http://www.scientificamerican.com/article/the-liberals-war-on-science/
- ↑ Polling the anti-GM vote
- ↑ Reaping the benefits: Science and the sustainable intensification of global agriculture. Chapter three
- ↑ Brain Dunning - Genetically Modified Organisms: Jeopardy or Jackpot?
- ↑ "Frankenfoods vs. the neo-Luddites"
- ↑ WHO - 20 questions on genetically modified foods.
- ↑ The GMO Population Cull … Getting Away With Murder
- ↑ The Prince of Wales: 'If that is the future, count me out'
- ↑ Deepak Chopra and Vandana Shiva Talk Seeds and GMOs
- ↑ Boycott Genetically Modified (GM) Foods, on janegoodall.org, 13-Sept-2014